Welcome to the Angers laboratory.
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Laboratory of Functional Architecture of Signal Transduction.


Our research program focuses on studying the molecular mechanism of signal transduction machineries.

Our interests are divided into three main themes:

1) The study of the signalling pathways activated by the Wnt and Hedgehog families of secreted glycoproteins.

2) The study of cell signalling activated by G Protein Coupled Receptors and Heterotrimeric G Proteins.

3) The molecular mechanisms underlying the functions of Cullin-RING E3 ubiquitin ligases.

We use a combination of biochemical and molecular biology approaches with new tools in proteomics and mass spectrometry to assess the function of specific proteins within protein complexes.


News: June 2015.

Lab manager and PDF positions available.

More info.


Congrats to Cherry for her publication in Science Signaling on the role of the PPFIA1-PP2A complex in Hedgehog signaling.




Stephane Angers Ph.D
Associate Professor
Leslie Dan Faculty of Pharmacy, Room 901
University of Toronto
144 College Street
Toronto, Ontario

Phone: 416-978-4939
Fax: 416-978-8511


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